Police recovered a fentanyl patch, needle, and syringe at the scene. Case 1 was a 35-year-old with no known history of drug use, who was found by his wife on the floor of his workshop. In all of these cases, the victim was a white male who died at home. We present 4 cases in which the source of fentanyl was transdermal patches and was injected. Death due to the intravenous injection of fentanyl extracted from transdermal patches has not been previously reported. Even after the prescribed application time has elapsed, enough fentanyl remains within a patch to provide a potentially lethal dose. The transdermal fentanyl system delivers a specific dose at a constant rate.
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